(a) Features of
silicon generated by microcontact printing followed by selective
etching. In the insert the surface was stamped twice.
electron microscope micrograph of fibrinogen adsorbed on a
patterned monolayer. A patterned hexadecanethiol self-assembled
monolayer on gold was formed by microcontact printing, and
remainder of the surface was covered by a monolayer of hexa
(ethylene glycol)-terminated alkanethiol [HS(CH2)11(OCH2CH2)6
OH]. Fibrinogen was adsorbed only to the methyl-terminated
regions (area 2) while no adsorption occured at ethylene
glycol-terminated regions (area 1).
scanning electron microscope micrograph demonstrates that
microcontact printing can be used for patterning the adsorption
of proteins at dimensions on the micron scale.
sensor for lipolytic enzymes .