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(a) Features of silicon generated by microcontact printing followed by selective etching. In the insert the surface was stamped twice.

 

(b) Scanning electron microscope micrograph of fibrinogen adsorbed on a patterned monolayer. A patterned hexadecanethiol self-assembled monolayer on gold was formed by microcontact printing, and remainder of the surface was covered by a monolayer of hexa (ethylene glycol)-terminated alkanethiol [HS(CH2)11(OCH2CH2)6 OH]. Fibrinogen was adsorbed only to the methyl-terminated regions (area 2) while no adsorption occured at ethylene glycol-terminated regions (area 1).

 

(c) Similar scanning electron microscope micrograph demonstrates that microcontact printing can be used for patterning the adsorption of proteins at dimensions on the micron scale.

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Capacitive sensor for lipolytic enzymes [24].

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